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OECD GUIDELINES FOR THE TESTING OF CHEMICALS. set out in this guideline allows for the pH-metric determination of log Pow values of for ionisable and.

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. Now the chemical potential of a solute X in this matrix S is: The coefficients can now be derived from experimental (log.). convert this into a s-profile p.

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In this case, the correct symbol for the resulting partition coefficient is log D pH 7.4. The assay starts with compound dissolved in DMSO.Log. P < 5. H-bond acceptors < 10 (the sum of N and O atoms without H attached). Présentation PowerPoint Last modified by: Standard Company.

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